trastuzumab -| ERBB2
pertuzumab -| ERBB2
ERBB2 -> ERBB2
erlotinib -| ERBB2
ERBB1 -> ERBB1
pertuzumab -| ERBB1
PLCg -> ERBB1
EGF -> ERBB1
erlotinib -| ERBB1
ERK1_2 -> p70S6K
AKT -> p70S6K
mTOR -> p70S6K
p70S6K -> p70S6K
AKT -> AKT
ERBB3 -> AKT
mTOR -> AKT
PDK1 -> AKT
ERK1_2 -> ERK1_2
ERBB3 -> ERK1_2
MEK1_2 -> ERK1_2
PDK1 -> ERK1_2
ERBB1 -> PDK1
ERBB3 -> PDK1
ERBB2 -> PDK1
PDK1 -> PDK1
PKCa -> PKCa
PLCg -> PKCa
ERBB1 -> MEK1_2
ERBB3 -> MEK1_2
MEK1_2 -> MEK1_2
ERBB2 -> MEK1_2
AKT -> mTOR
mTOR -> mTOR
ERBB3 -> ERBB3
HRG -> ERBB3
pertuzumab -| ERBB3
erlotinib -| ERBB3
ERBB1 -> PLCg
ERBB3 -> PLCg
ERBB2 -> PLCg
PLCg -> PLCg
$AKT: (((PDK1 | mTOR) | AKT) | ERBB3)
$ERBB1: (((ERBB1 & !(erlotinib | pertuzumab)) | (PLCg & !(erlotinib | pertuzumab))) | (EGF & !(erlotinib | pertuzumab)))
$ERBB2: (ERBB2 & !((trastuzumab | pertuzumab) | erlotinib))
$ERBB3: ((ERBB3 & !(erlotinib | pertuzumab)) | (HRG & !(erlotinib | pertuzumab)))
$ERK1_2: (((PDK1 | ERK1_2) | ERBB3) | MEK1_2)
$MEK1_2: (((ERBB3 | ERBB2) | ERBB1) | MEK1_2)
$PDK1: (((ERBB2 | PDK1) | ERBB3) | ERBB1)
$PKCa: (PLCg | PKCa)
$PLCg: (((ERBB3 | ERBB1) | ERBB2) | PLCg)
$mTOR: (AKT | mTOR)
$p70S6K: (((ERK1_2 | mTOR) | p70S6K) | AKT)